The Eastern City University Medical Department Affiliated Hospital, located in a marginal area, has gained nationwide fame due to the extraordinary 'Saeki-style' mitral valve repair surgery performed by Professor Kiyoshi Saeki (played by Masanobu Uehara), whose black hemostatic forceps add a touch of mythical prestige to his persona. In stark contrast stands the Dihua University Hospital Affiliated Hospital, whose overall strength far surpasses that of Eastern City University. Here, Professor Keisuke Nishizaki (played by Kōsuke Ichikawa) is in fierce competition with Professor Saeki for the presidency of the Japanese Society of Comprehensive Surgery. To this end, Nishizaki sends his star pupil, Gōta Takashina (played by Kōtarō Koizumi), to infiltrate the enemy camp, attempting to undermine Saeki’s position with the latest medical equipment. However, under Saeki’s command is a troublesome figure that gives all doctors a headache. This individual, Seijirō Tokai (played by Kazunari Ninomiya), saves numerous lives with his exceptional surgical skills but is known as a terrifying devil doctor due to his sharp tongue and dark personality. With undisclosed intentions, Tokai becomes entangled in the conflict between Saeki and Nishizaki...