In the future world, the demon party infected with the X virus carries the powerful Red Shield, appearing in every corner of the Earth. In just seven days, half of the planet's territory has fallen. People are displaced, hiding in the last refuge and struggling to survive. Dr. Nambu (played by Goro Kinugasa) from the International Science and Technology Office (ISO) discovers a mysterious stone that can grant certain individuals immense power, and the enhanced super warriors become the perfect candidates to stop the demon party. After that, Ken Wakakusa (played by Tori Matsuzaka), Jun Otsuki (played by Ayame Goriki), Jinpei Otsuki (played by Ryosuke Hamada), and Ryu Nakani (played by Ryohei Suzuki) are discovered by ISO and undergo a series of unimaginable training to grow into scientific ninjas who battle against the demon party. After one battle, Ken's old friend George Asakura (played by Go Ayano) joins them, and they are ordered to protect the demon party's fleeing leader Ilia (played by Shido Nakamura) in order to obtain details about the Last Suicide plan. Faced with this deeply resentful enemy, the hearts of Ken and George subtly change...