It tells the story of the scientific research team that suffered a plane crash and fell into an unmanned iceberg during the expedition, and the population research journey turned into a fatal journey. Song Wu (played by Guo Jindong), a survivor of the scientific research team, was chased by a giant wolf in the snow mountain on the way to lead everyone to escape, and his daughter Jingwen (played by Liu Yihan), who has autism, was taken hostage by the giant wolf. In order to save his daughter, he decided to brave the wolf's den and start a life-and-death battle with the mutant giant wolf. The man-eating wolves are approaching step by step, their companions are reduced to "wolf's mouths" one after another, the giant wolves are besieged, the snowy mountains are surviving, and multiple threats are escalating, and a thrilling battle between people, disasters and giant beasts begins. In the face of this life-and-death test, will everyone be able to escape? Who loses and who wins in the battle between man and beast in the end?